An AAA family tree.
نویسنده
چکیده
منابع مشابه
Aaa Risk Assessment-integrating Morphologic, Biomechanic, Molecular and Clinical Risk Factors to Improve Decision Making
In an effort to improve abdominal aortic aneurysm (AAA) rupture risk assessment several studies have identified demographic, morphometric, thrombus-related, biomechanic, and biological characteristics that associate with rupture risk. However, it is unlikely that parameters from either the biomechanics or the biology aspect of AAA rupture alone can capture the multifactorial pathology of AAA ru...
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Dyneins are large protein complexes that act as microtubule based molecular motors. The dynein heavy chain contains a motor domain which is a member of the AAA+ protein family (ATPases Associated with diverse cellular Activities). Proteins of the AAA+ family show a diverse range of functionalities, but share a related core AAA+ domain, which often assembles into hexameric rings. Dynein is unusu...
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Two AAA family ATPases, NSF and p97, have been implicated in membrane fusion during assembly and inheritance of organelles of the secretory pathway. We have now investigated the roles of AAA ATPases in membrane fusion during assembly of the peroxisome, an organelle outside the classical secretory system. Here, we show that peroxisomal membrane fusion in the yeast Yarrowia lipolytica requires tw...
متن کاملRecommendations on screening for abdominal aortic aneurysm in primary care.
CMAJ | SEPTEMBER 11, 2017 | VOLUME 189 | ISSUE 36 E1137 A n abdominal aortic aneurysm (AAA) results from a weakening in a section of the aortic wall in the abdomen, which bulges because of pressure from blood flow to form an aneurysm.1 The aneurysm may grow and eventually rupture, causing death from hemorrhage.1 It is estimated that each year, 20 000 Canadians receive a diagnosis of AAA, and th...
متن کاملFundamental Characteristics of AAA+ Protein Family Structure and Function
Many complex cellular events depend on multiprotein complexes known as molecular machines to efficiently couple the energy derived from adenosine triphosphate hydrolysis to the generation of mechanical force. Members of the AAA+ ATPase superfamily (ATPases Associated with various cellular Activities) are critical components of many molecular machines. AAA+ proteins are defined by conserved modu...
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عنوان ژورنال:
- Journal of cell science
دوره 114 Pt 9 شماره
صفحات -
تاریخ انتشار 2001